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| Clinical Results |
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| Clinical Trial Updates |
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Non-expanded adipose stromal vascular fraction cell therapy
for multiple sclerosis |
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The stromal vascular fraction (SVF) of adipose tissue is known to contain mesenchymal stem cells (MSC),
T regulatory cells, endothelial precursor cells, preadipocytes, as well as anti-inflammatory M2 macrophages. Safety of autologous adipose tissue implantation is supported by extensive use of this procedure in cosmetic surgery, as well as by ongoing studies using in vitro expanded adipose derived MSC.
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Cell-Assisted Lipotransfer for Cosmetic Breast Augmentation:
Supportive Use of Adipose-Derived Stem/Stromal Cells |
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In this study, 40 patients with healthy thoraxes and breasts underwent CAL for purely cosmetic breast augmentation.
Patients undergoing breast reconstruction for inborn anomaly or after mastectomy were not included. At this writing, 19 of these 40 patients have been followed for more than 6 months, and the maximum follow-up period has been 42 months. All the patients were Japanese women with a mean body mass index (BMI) of 19.1, 1.9. Their ages varied from 20 to 62 years (mean, 35.8, 9.1).
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| Treatment of amyotrophic lateral sclerosis patients by autologous bone marrow-derived hematopoietic stem cell transplantation: a 1-year follow-up |
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Over the past few years, stem cell research has expanded greatly as a tool for developing potential new therapies to
treat incurable neurodegenerative diseases. Stem cell transplantation has been effective in several animal models, but the underlying restorative mechanisms are still unknown. Several mechanisms, such as cell fusion, eurotrophic factor release, endogenous stem cell proliferation and
transdifferentiation, may explain the positive therapeutic
results, in addition to replacement of lost cells |
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| Adipose-Derived Stem Cells for Regenerative Medicine |
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| Tissue engineering and regenerative medicine is a multidisciplinary science that has evolved in parallel with recent biotechnological advances. It combines biomaterials, growth factors, and stem cells to repair failing organs.1 Material scientists can now fabricate biocompatible scaffolds with a wide range of physical parameters, combining mechanical integrity with high porosity to promote cell infiltration and angiogenesis... |
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